Noggin Expands Neural Stem Cells in the Adult Hippocampus

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Noggin expands neural stem cells in the adult hippocampus.

New neurons are added to the adult hippocampus throughout life and contribute to cognitive functions, including learning and memory. It remains unclear whether ongoing neurogenesis arises from self-renewing neural stem cells (NSCs) or from multipotential progenitor cells that cannot self-renew in the hippocampus. This is primarily based on observations that neural precursors derived from the su...

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ژورنال

عنوان ژورنال: Journal of Neuroscience

سال: 2008

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.3314-07.2008